OSIRIS can also improve your existing methods. You can fix your own criteria in terms of quality of separation (resolution), analysis time and/or robustness. You can evaluate how sensitive this method is to small variations in the conditions or to shorten the analysis time without sacrificing resolution. OSIRIS allows you also to focus on the separation of target compounds.  

The CRIT parameter is a unique tool which allows to select the most favorable composition zones for ternary and quaternary mobile phases.