Finish first with Onyx™

The monolithic nature of this product will give scientists opportunities not common with particle-based columns.


New: C18 also available in 150 x 0.05 mm and 150 x 0.2 mm, C8 also available in 150 x 0.1 mm

Novel HPLC technology = Novel HPLC solutions

The monolithic silica structure of Onyx™ provides very unique separation options vs. particle-based columns. Onyx is composed of a bimodal pore structure consisting of macropores and mesopores. The optimized ratio of these two pores makes possible separations at significantly high flow rates (up to 9mL/min) and at extremely low backpressures…ultimately leading to extremely high sample throughput.

High efficiency

In addition to the advantage of high throughput, Onyx columns deliver high efficiency separations and can be coupled together in series to produce the extreme plate counts needed to separate very complex mixtures.

Dilute & shoot

Complex mixtures coupled with dirty matrices, such as serum samples encountered in the pharmaceutical/biotechnology industry, are quite difficult and time-consuming to analyze. With Onyx however, you have the option to “dilute-and-shoot” your sample directly onto the column because it won’t clog due to the macroporous system or cause high backpressures.

Flow rate flexibility

Another unique feature is the ability to use flow rate as parameter for optimizing separations. Onyx columns are responsive to changes in flow rate and can be changed mid run to reduce total run time when certain compounds elute much later. This type of flow rate flexibility gives many options for optimization.


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