Lux - Simplified chiral LC

Lux is a new line of polysaccharide-based chiral stationary phases to provide a straightforward approach to enantiomeric recognition and separation through HPLC (NP and RP) and SFC.

Lux columns are offered with two chiral stationary phases (CSPs), both of which use coated derivatized cellulose as the chiral selector (available in 3um and 5um particle).

 

Benefits of Lux:

- High loading capacity

- Stable, reproducible phases

- Stability in variety of solvents, including SFC conditions

- Stable until 300bar column backpressure

Lux™ Amylose-2 - NEW

This unique phase widens the range of enantioselectivity
The chiral selector is an amylose tris(5-chloro-2-methylphenylcarbamate).

 

The selectivity of Lux Amylose-2 is an complement to your chiral screen. Lux Amylose-2 uses a unique halogenated derivative that offers a broad range of enantioselectivity, previously unavailable commercially.

Lux Cellulose-2 - Advanced chiral selector provides a unique range of enantioselectivity

Lux  Cellulose-2 incorporates an advanced halogenated derivative, leading to unique enantioselectivity compared to previously commercialized cellulose phases

 

Uses the chiral selector cellulose tris(3-chloro-4-methylphenylcarbamate):
It has been established that the introduction of either electron-donating or electron-withdrawing groups, such as chlorine, tends to improve the optical resolution abilities of CSPs with phenylcarbamate derivatives. In addition, substitution at the meta or para position on the phenyl moiety is considered more beneficial than at the ortho position to establish higher chiral recognition1.

This unique derivatization of Lux Cellulose-2 makes it an ideal CSP to add to all chiral screening protocols and provides excellent complementary selectivity to Lux Cellulose-1 in many applications.

 

Studies have shown that for a set of 14 racemates of varying properties, the 3-chloro-4-methylphenylcarbamate derivative of cellulose was one of the few commercialized phases that separated all 14 compounds with α >1.01.

 

1 Bezhan Chankvetadze, Eiji Yashima, Yoshio Okamoto, J. Chromatography, 670 (1994) 39-49

Lux Cellulose-1 - The new alternative for dimethylphenylcarbamate separations

Lux  Cellulose-1 features a classical chiral selector used industry-wide for many enantiomeric separations. (guaranteed replacement to CHIRALCEL® OD® family)

 

Uses the chiral selector cellulose tris(3,5-dimethylphenylcarbamate):
This particular chiral selector has well established abilities in resolving a wide range of racemates. Lux Cellulose-1 provides enhanced resolution for a variety of applications compared to similar CSPs.

 

Send E-Mail

Schlieren:

Tel +41 44 732 31 31

Fax +41 43 260 95 36

Echallens:

Tel +41 21 625 58 10

Fax +41 43 260 95 36