Kinetex™ - UHPLC Performance on ANY HPLC System

You can immediately improve resolution, throughput, and sensitivity as well as reduce solvent consumption. No longer restricted by the HPLC/UHPLC system divide, you can develop high performance LC methods on any instrument and transfer them anywhere.

Ultra-high performance on any LC with the New Kinetex Phases XB-C18 & C8

Kinetex XB-C18 and Kinetex C8 bring the advantages of ultra-high liquid chromatography performance (UHPLC) within standard HPLC operating pressures to a growing list of applications. Kinetex core-shell technology meets researchers’ need to improve results and increase productivity without large capital expenditures.


The new Kinetex XB-C18 provides a unique selectivity, incorporating two iso-butyl side chains at the base of the C18 ligand to reduce secondary interactions with residual silanols. These columns deliver enhanced separation and peak shape of basic compounds under neutral and acidic pH conditions. In comparison studies with other C18 columns, this new Kinetex phase has produced differences in peak elution order and improved separation of co-eluting compounds.


The new Kinetex C8 phase meets the United States Pharmacopeia (USP) specifications for Classification Code L7, enabling laboratories using L7 columns to realize the benefits of Kinetex core-shell technology while staying compliant with USP-allowable adjustments.

The new Kinetex core-shell columns are available in two particle sizes – 2.6- and 1.7- micron – and in variety of column dimensions.

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Sub-2µm Efficiency, Low Backpressure

With the efficiency of a sub-2 µm column and a typical operating backpressure less than 400 bar (Kinetex 2.6 µm) , you can achieve the promise of ultra-high performance on any LC System.


Lower Levels of Detection

The combination of the small particle size, narrow particle size distribution, and the significantly shorter diffussion path results in much higher column efficiencies and increased chromatographic resolution. the increased efficiencies provide an immediate benefit on sensitivity.


Maximize Throughput

For the ultimate sample throughput demands, Kinetex™ columns provide the efficiency needed to significantly reduce run times. In this separation of 13 ketones, a 20-fold increase in productivity is accomplished while still maintaining resolution.


Replace Sub-2 µm Columns For Higher Efficiency

For users of higher pressure capable instruments who want the highest level of efficiency, Phenomenex introduce the Kinetex 1.7 µm column - the first sub-2 µm core-shell particle available on the market. 


Orthogonal Selectivity

To provide alternative and orthogonal selectivity phases, Kinetex™ columns are available in 3 selectivities: C18, PFP (Pentafluorophenyl), and HILIC* (Hydrophilic Interaction Liquid Chromatography), for resolution of a wide range of compounds from polar to hydrophobic, aromatic, and isomers.